Ron Kamonohashi, the best student in the history of the elite Detective Training Academy BLUE, has been living as a recluse since BLUE expelled him five years ago. His situation changes drastically when police detective Totomaru Isshiki, following the advice of a senior colleague, seeks him out for help with a criminal case that has remained unsolved for months. Ron reluctantly agrees to help Totomaru and uses his phenomenal intuition to discover the culprit in less than a day. However, it appears that Ron suffers from a mysterious condition that can cause those around him to lose their lives. To Ron's great surprise, Totomaru manages to save the life of someone whom Ron put in jeopardy. As the unlikely duo starts solving crimes one after another, BLUE sends operatives after them. Fighting against various obstacles, Ron and Totomaru must join forces if they want to survive and see justice prevail.